LewisÌýBaker
About
I am a first-yearÌýÌýgraduate student currently working withÌýÌýon methods for analyzing trajectories of single molecules. I received a B.S. in Mathematical Biology from the University of Pittsburgh in 2015. In my spare time I bake bread, play guitar, and climb.
Contact
Email: lewis.r.baker coloradoedu
Research
I am interested in developing methods to estimate chemical observables from experiments and simulations. My current work involves analysis of single molecule trajectories of a class of biomolecules calledÌýmembrane targeting proteins. These proteins bind to constituent lipids of cell membranes and are involved in numerous biochemical processes, including chemotaxis, collective cell migration, and cell proliferation/growth.
Central to understanding the role of membrane targeting proteins in these processes is the ability to measure the number of high-affinity protein-lipid contacts under a given set of conditions. To this end, I am developing tools to infer details about the binding behavior of proteins based on their movement.
Teaching
Teaching Assistant:
APPM1350, Calculus 1 for Engineers (Fall 2015)
APPM1360, Calculus 2 for Engineers (Spring 2016, Summer 2016)
COEN1360, Calculus 2 Workgroup (Spring 2016)
Publications
Garlena, R.A., Lennox, A.L.,ÌýBaker, L.R.,, Parsons, T.E., Weinberg, S.M., Stronach, B.E..ÌýPvr receptor tyrosine kinase promotes tissue closure by coordinating corpse removal and epidermal zippering,ÌýDevelopment,Ìý142(19):3403-15, 2015. DOI: 10.1242/dev.122226.