Published: Nov. 20, 2013

While young children sleep, connections between the left and the right hemispheres of their brain strengthen, which may help brain functions mature, according to a new study by the University of Colorado Boulder.

The research team鈥攍ed by Salome Kurth, a postdoctoral researcher, and Monique LeBourgeois, assistant professor in integrative physiology鈥攗sed electroencephalograms, or EEGs, to measure the brain activity of eight sleeping children multiple times at the ages of 2, 3 and 5 years.

鈥淚nterestingly, during a night of sleep, connections weakened within hemispheres but strengthened between hemispheres,鈥 Kurth said.

Scientists have known that the brain changes drastically during early childhood: New connections are formed, others are removed and a fatty layer called 鈥渕yelin鈥 forms around nerve fibers in the brain. The growth of myelin strengthens the connections by speeding up the transfer of information.

Maturation of nerve fibers leads to improvement in skills such as language, attention and impulse control. But it is still not clear what role sleep plays in the development of such brain connections.

In the new study, appearing online in the journal Brain Sciences, the researchers looked at differences in brain activity during sleep as the children got older and differences in brain activity of each child over a night鈥檚 sleep. They found that connections in the brain generally became stronger during sleep as the children aged.听 They also found that the strength of the connections between the left and right hemispheres increased by as much as 20 percent over a night鈥檚 sleep.

鈥淭here are strong indications that sleep and brain maturation are closely related, but at this time, it is not known how sleep leads to changes in brain structure,鈥 Kurth said.

Future studies will be aimed at determining how sleep disruption during childhood may affect brain development and behavior.

鈥淚 believe inadequate sleep in childhood may affect the maturation of the brain related to the emergence of developmental or mood disorders,鈥 Kurth said.

Other co-authors of the study include Thomas Rusterholz, a former CU-Boulder postdoctoral researcher; and Peter Achermann, a sleep researcher at the University of Zurich in Switzerland.

The study was funded by the National Institute of Mental Health, Sepracor Inc. and the Swiss National Science Foundation.

Contact:
Salome Kurth, 303-492-4584
Salome.Kurth@colorado.edu
Laura Snider, CU media relations, 303-735-0528
Laura.Snider@colorado.edu

鈥淭here are strong indications that sleep and brain maturation are closely related, but at this time, it is not known how sleep leads to changes in brain structure,鈥 said Salome Kurth, a postdoctoral researcher in integrative physiology.