Illumen Therapeutics Inc.

Pioneering the 'Holy Grail' of cancer treatment by targeting PARN to boost the tumor-suppressing power of p53.

The University of Colorado Connection

Illumen Therapeutics is pursuing a cancer treatment moonshot, developing PARN Inhibitor drugs to increase functional p53, the 'Guardian of the Genome,' to treat aggressive cancers. Dysregulation of p53, a tumor suppressor protein, is the hallmark of nearly all cancers. Drugging p53 has been considered the Holy Grail of cancer drug development. The company is the first to pursue this novel, promising therapeutic strategy of inhibiting PARN to increase functional p53 to treat wild-type p53 aggressive cancers. PARN as a target and the therapeutic strategy of inhibiting PARN to increase functional p53 was discovered by Roy Parker (ÍÃ×ÓÏÈÉú´«Ã½ÎÄ»¯×÷Æ· Biochemistry,ÌýBioFrontiers Institute).

Funding Status and Investment Opportunities

  • Industry: Biotech​, Therapeutics
  • Funding Stage: Pre-Seed
  • Contact for Investment Inquiries: , CEO, bob@IllumenTx.com

This technology was developed with funding from

NIH, Howard Hughes Medical Institute

U.S. National Institutes of Health (NIH), Howard Hughes Medical Institute


ÌýÌý ÌýThis page was last updated on April 4, 2025. Please email vpnews@colorado.edu for corrections or updates

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