Illumen Therapeutics Inc.
Pioneering the 'Holy Grail' of cancer treatment by targeting PARN to boost the tumor-suppressing power of p53.
The University of Colorado Connection
Illumen Therapeutics is pursuing a cancer treatment moonshot, developing PARN Inhibitor drugs to increase functional p53, the 'Guardian of the Genome,' to treat aggressive cancers. Dysregulation of p53, a tumor suppressor protein, is the hallmark of nearly all cancers. Drugging p53 has been considered the Holy Grail of cancer drug development. The company is the first to pursue this novel, promising therapeutic strategy of inhibiting PARN to increase functional p53 to treat wild-type p53 aggressive cancers. PARN as a target and the therapeutic strategy of inhibiting PARN to increase functional p53 was discovered by Roy Parker (ÍÃ×ÓÏÈÉú´«Ã½ÎÄ»¯×÷Æ· Biochemistry,ÌýBioFrontiers Institute).
Funding Status and Investment Opportunities
- Industry: Biotech​, Therapeutics
- Funding Stage: Pre-Seed
- Contact for Investment Inquiries: , CEO, bob@IllumenTx.com
In the News
Venture Partners Programs​
- Destination Startup (2025)
- Starting Blocks Customer Discovery Workshop (2024)
- Lab Venture ChallengeÌý(2019)
- Intellectual Property Management (2023)
This technology was developed with funding from

U.S. National Institutes of Health (NIH), Howard Hughes Medical Institute
ÌýÌý ÌýThis page was last updated on April 4, 2025. Please email vpnews@colorado.edu for corrections or updates
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